Gynecomastia and Tamoxifen (Nolvadex) (Can be found in any pharmacy or drug store)

If you suffer from man boobs, you are probably wondering if any drugs exist that can help you treat the condition. This is of course, if you would rather not have surgery. Fortunately for you, medical research shows that there are drugs that can be used for male breast reduction. It doesn’t matter if the male has pubertal gynecomastia or developed extra male breast tissue as an adult.

So what drugs can possibly be used for the treatment of gynecomastia?

There are many, but in this article, we will focus on tamoxifen.

Tamoxifen is a medicine that was originally developed for the treatment of breast cancer. The effect of the medication is that it prevents the binding between estrogen and its receptor. Therefore, this prevents the breast cancer cells from growing.
10 to 20 mg per day is usually enough.

For gynecomastia, tamoxifen has been used in several applications. One of the popular brand names that tamoxifen is sold under is Nolvadex. It has been used to treat gynecomastia in men who developed gynecomastia as a result of undergoing prostate cancer treatment. In one study, ten patients were monitored for a certain time period while they took tamoxifen. Most of the patients had smaller breasts at the end. Bodybuilders also use the drug to prevent gynecomastia that is caused as a result of steroid use. Now listen to this! Tamoxifen is also used to prevent chest fat in sex offenders who are undergoing chemical castration. Now, do we really care if sex offenders have gynecomastia? I ‘ll let you think about that one.

Tamoxifen could potentially be an excellent alternative to gynecomastia surgical treatment. You should only take it if you are in good health. Consult your physician for more information.

Nolvadex (Tamoxifen) ------> Can be found in any pharmacy or drug store

Nolvadex is the most well known and widely used Anti Estrogen.
Nolvadex works by binding to the estrogen receptors in the body, preventing estrogen from binding to these sites. Hence, why Nolvadex is referred to also as an 'estrogen blocker' or by it's more medical term: SERM (Selective Estrogen Receptor Modulator).


In women Nolvadex is used as a breast cancer medication, blocking estrogen is vital to stop cancer spread.

In men Nolvadex usage is particularly interesting as it is known to be used by many athletes, bodybuilders and fitness enthusiasts mainly to prevent gynecomastia (formation of female like breast tissue in men) due to steroids use. Some men may develop gynecomastia even without drug use, actually gynecomastia is extremely widespread among men and particularly adolescents. In many cases gynecomastia symptoms in adolescents may go away on their own though sometimes they may form breast tissues.
10 to 20 mg per day is usually enough.

Steroids and testosterone are known to aromatise to estrogen, by blocking the estrogen receptors in breast tissue, Nolvadex prevent that harmful estrogen to cause gynecomastia (bitch tits) in men.

Nolvadex is also used to promote the secretion of LH (Luteinizing hormone). LH is a very important hormone for both women and men. In men, LH is responsible for the production of testosterone (the male hormone) by the Leydig cells of the testes in males. Athletes and bodybuilders who use anabolic steroids, testosterone and other performance enhancing drugs, frequently use Nolvadex in order to block estrogen that result as a side effect from using drugs.

Since Nolvadex also acts as LH stimulator, much like Clomid does. It
encourages natural testosterone production in men. Many men prefer Nolvadex over Clomid
for that purpose, in fear that Clomid causes many side effects while Nolvadex may cause less or none. Some prefer the combined use of Nolvadex and Clomid during PCT (Post Cycle Therapy).

La Gynécomastie et Tamoxifène (Nolvadex) --------> (Dans n'importe quelle pharmacie)

Nolvadex est composé de citrate de tamoxifène. Ce n’est pas un stéroïde anabolisant mais un anti-oestrogène par voie orale.

Nolvadex est le plus puissant des anti-oestrogènes et le préféré des culturistes.

Il permet d’éviter les phénomènes de féminisation qui surviennent fréquemment à la fin d’un cycle de stéroïdes anabolisants comme la gynécomastie ainsi qu’une rétention graisseuse et aqueuse au niveau des hanches ou des seins.

En effet, en fin de cycle, la plupart des stéroïdes anabolisants s’aromatisent en hormone oestrogène, provoquant l’apparition de ces symptômes.

Le citrate de tamoxifene a la faculté de bloquer les récepteurs d’oestrogène, empêchant ainsi l’oestrogène d’agir et de provoquer ces phénomènes.

De nombreux culturistes utilisent Nolvadex avant une compétition car outre le fait qu’il empêche la gynécomastie, le fait de diminuer la rétention d’eau et de graisses aide le culturiste à obtenir un physique sec.

Enfin le citrate de tamoxifene a la faculté d’augmenter la production de testostérone endogène, ce qui est particulièrement apprécié par les culturistes en fin de cycle.

En effet, en fin de cycle, la production naturelle de testostérone est généralement à un niveau assez bas car durant tout le cycle, les anabolisants pris l’ont inhibée et remplacée.
Il peut ainsi survenir de graves accidents après l’arrêt d’un cycle de stéroïdes si la production de testostérone naturelle n’est pas ramenée à un niveau normal.

Nolvadex permet de prévenir ce genre d’accident en relançant la production de testostérone dans les testicules.
Le principal inconvénient de Nolvadex est qu’il diminue les gains produits par les anabolisants pris.C’est la raison pour laquelle bon nombre de sportifs ne l’utilisent que lorsqu’ils y sont obligés afin d’éviter la gynécomastie.
En ce qui concerne les effets secondaires de ce produits, ils se limitent généralement à quelques nausées et à quelques troubles de la vue.
Enfin il faut noter que si Nolvadex bloque les récepteurs d’oestrogène et empêche l’oestrogène d’agir, il n’élimine pas cette hormone du corps. Ce qui veut dire qu’après l’arrêt du traitement par Nolvadex, une quantité importante d’hormone oestrogène restée inactive va pouvoir soudain se fixer aux récepteurs nouvellement libérés, causant les effets féminisants que l’on avait évité jusque là.

C’est un phénomène que l’on peut prévenir en combinant Nolvadex avec un autre anti-oestrogène puissant comme Proviron, pour une efficacité radicale.
10 à 20 mg par jour suffisent habituellement pour éviter les gynécomastie.

Nolvadex se présente en flacons de 60 ou 250 comprimés de 10 ou 20 mg.

Nolvadex peut être associé avec les anabolisants les plus forts comme la testostérone ou le Déca pour éviter la gynécomastie.
Nolvadex sera d’une efficacité redoutable combiné avec du Proviron.

Fiche technique : Nolvadex.
Molécule : citrate de tamoxifène.
Voie : orale.
Catégorie : anti-oestrogène.
Effets positifs : stoppe la gynécomastie. Effets négatifs : diminue la prise de masse. Dose : 10 mg/jour.
Force : *
Masse : *
Danger : *

Extract of some articles And Medical research

Tamoxifen has shown some promising results in the management of gynecomastia.
Here's a medical article published on April 2006 by
Department of Surgery, University Hospital of Wales, UK

gynecomastia affects half of the male population at some stage in their life. Only a small proportion of them would require treatment for cosmetic appearance or to relieve pain and tenderness. Recently, tamoxifen has shown some promising results in the management of gynecomastia. To assess the efficacy of tamoxifen, we carried out a retrospective study of all men treated for gynecomastia with particular emphasis on those treated medically. Men with painful gynecomastia were given 10 mg of tamoxifen for 3 months. Response to treatment was categorised as good, moderate and no response. Thirteen men (median age 36) were placed on tamoxifen. Ten patients responded well to tamoxifen. One patient developed calf tenderness and stopped the medication. No other adverse effects were reported. Two patients could not be followed up. Tamoxifen appears safe and effective in men with painful idiopathic or physiological gynecomastia and should be considered as an initial option before contemplating surgery.




Tamoxifen treatment for pubertal gynecomastia.
Article published on International Journal Adolsec Med Health 2003 Oct-Dec
Section of Adolescent Medicine, Department of Pediatrics, Hacettepe University Faculty of Medicine, 06100 Ankara-Turkey

We evaluated the efficacy of the tamoxifen treatment in 37 patients with pubertal gynecomastia. All had distinct, easily palpable breast swellings with a diameter of over three cm. Pain, tenderness, and swelling associated with gynecomastia were reported by six patients. Eight of the patients were obese. One patient also suffered from varicocele. Pain and size reduction was seen in all patients with tamoxifen treatment. No long-term side effects of tamoxifen were observed. The dose of tamoxifen was increased in three patients due to poor response. Two of the treatment group had recurrence problem at follow-up. We did not need to refer any patient to surgery. Tamoxifen treatment is relatively non-toxic, may be beneficial and we think it should be considered for pubertal gynecomastia.
Link to original article on pubmed:




Management of physiological gynecomastia with tamoxifen.
Article published on February 2004
Professorial Unit of Surgery, Department of Surgery, Nottingham City Hospital, Nottingham UK

AIMS: We aimed to confirm suggestions that tamoxifen therapy alone may resolve physiological gynecomastia. METHODS: A prospective audit of the outcome of tamoxifen routinely given to men with physiological gynecomastia was carried out at Nottingham. Men referred with gynecomastia had clinical signs recorded, e.g., type (diffuse 'fatty' or retro-areolar 'lump'), size and possible aetiology. They were offered oral tamoxifen 20mg once daily for 6-12 weeks. On follow-up patients were assessed for complete resolution (CR), partial resolution where patient is satisfied with outcome (PR) or no resolution (NR). Success was either CR or PR. RESULTS: Thirty-six men accepted tamoxifen for physiological gynecomastia. Median age was 31 (range 18-64). Tenderness was present in 25 (71%) cases. Sixteen men (45%) had 'fatty' gynecomastia and 20 had 'lump' gynecomastia. Tamoxifen resolved the mass in 30 patients (83.3%; CR=22, PR=8) and tenderness in 21 cases (84%; CR=0, PR=0). Lump gynecomastia was more responsive to tamoxifen than the fatty type (100% vs. 62.5%; P=0.0041). CONCLUSIONS: Oral tamoxifen is an effective treatment for physiological gynecomastia, especially for the lump type.




Testosterone and estradiol levels in male gynecomastia. Clinical and endocrine findings during treatment with tamoxifen.
Article published on November 1984
Deutsche medizinische Wochenschrift

Oestradiol-(E2) levels in serum were significantly higher in a group of 91 males with gynecomastia than in a control group. The levels were highest in patients with testicular tumour, hyperprolactinaemia and idiopathic gynecomastia. In gynecomastia of puberty and primary or secondary hypogonadism, the E2 level was within normal limits, but the testosterone/oestradiol ratio was significantly reduced. Tamoxifen, at a daily dose of 20 mg, was administered over 2-4 months to 16 patients with gynecomastia. Of twelve patients with painful gynecomastia ten became painfree. gynecomastia regressed partially or completely in 14 patients, in only 2 was it unchanged. There was no recurrence of gynecomastia after discontinuing tamoxifen. Side-effects did not occur. It is concluded that tamoxifen is a promising alternative to the surgical treatment of gynecomastia.




Treatment of gynecomastia with tamoxifen: a double-blind crossover study.
Article published on August 1986
Metabolism: clinical and experimental

Benign asymptomatic or painful enlargement of the male breast is a common problem, postulated to be due to an increased estrogen/testosterone ration or due to increased estrogenic or decreased androgenic stimulation via estrogen or androgen receptor interactions. Treatment at present consists of analgesic medication or surgery. However, treatment directed against the preponderance of estrogenic stimulation would seem to represent a more specific form of therapy. In the present double-blind crossover study, one-month courses of a placebo or the antiestrogen tamoxifen (10 mg given orally bid) were compared in random order. Seven of ten patients experienced a decrease in the size of their gynecomastia due to tamoxifen (P less than 0.005). Overall, the decrease for gynecomastia for the whole group was significant (P less than 0.01). There was no beneficial effect of placebo (P greater than 0.1). Additionally, all four patients with painful gynecomastia experienced symptomatic relief. There was no toxicity. The reduction of breast size was partial and may indicate the need for a longer course of therapy. A followup examination was performed in eight out of ten patients nine months to one year after discontinuing placebo and tamoxifen. There were no significant changes from the end of the initial study period except for one tamoxifen responder who developed a recurrence of breast tenderness after six months, and one nonresponder who demonstrated an increase in breast size and a new onset of tenderness after ten months. Therefore, antiestrogenic treatment with tamoxifen may represent a safe and effective mode of treatment for selected cases of cosmetically disturbing or painful gynecomastia.

Gynecomastia Without Surgery - Solution For Those That Don't Want Surgery

If you don't want to go through with an operation its perfectly understandable. Surgery is extremely expensive. Surgeons fee runs from $2500 to $3200, operating room fees runs from $900 to $1500, and anesthesia is about $250 an hour. This isn't including the additional costs of compression vests, lab tests, and prescriptions. Your insurance will most likely not cover this as its looked at as cosmetic surgery. There are more practical routes that you can take. Described below are ways to realistically lose your boobs without surgery.

Diet
There are numerous causes for gynecomastia. These include puberty, marijuana use, and obesity. If your overweight, the extra fat in your body causes it to produce more estrogen, which as you know produces your breasts. One such was to combat this problem is to adopt a healthier diet into your lifestyle.

If you're over the age of 25, chances are that your metabolism is starting to slow down. This means that you can't eat certain foods as much as you used to. Limit your the portion sizes of your meals. Most people eat a lot more than what their body needs. If you drink alcohol, cut down on it. One beer has over 100 calories which is about as equivalent to one cookie. Aim at eating "good carbohydrates" which include fruits, vegetables, and whole grains. These types of foods are filling, nutritious, and are low in calories.

Exercise
Cardio is important because it will burn the fat off your chest. Since your going for fat loss, you want to do cardio 4 times per week for at least 30 minutes. You should also do strength training exercises to tone up your pecs muscles. I highly recommend push ups because they effectively work your pecs but also work you shoulders. This is important because when your shoulder are tone, it will pull the skin tighter around your chest.

Important Points To Note
Although these are things to adopt if you want to lose your gynecomastia without surgery, the most important thing you should be focusing on is balancing out your hormones. This is because you can't fully lose your boobs without solving this issue. Once your body produces the proper amount of testosterone and estrogen, dieting and exercise will burn off your boobs, using Tamoxifen (Nolvadex ®) .